百濟神州(06160.HK)將在ASCO年會上展示豐富且成熟的腫瘤學藥物組合臨牀數據
格隆匯5月27日丨百濟神州(06160.HK)2022年5月27日宣佈,公司將在當地時間2022年6月3日至6月7日於芝加哥舉行的美國臨牀腫瘤學會(ASCO)年會上展示其豐富的實體瘤和血液腫瘤藥物組合中的8項研究數據報吿。
此次展示的數據重點包括BTK抑制劑百悦澤®(澤布替尼)的最新臨牀數據:百悦澤®對比伊布替尼用於治療華氏巨球蛋白血癥患者的3期ASPEN臨牀試驗的長期安全性和有效性結果,中位隨訪時間為43個月 ;百悦澤®聯合奧妥珠單抗對比奧妥珠單抗單藥治療復發╱難治性濾泡性淋巴瘤患者的2期ROSEWOOD臨牀試驗的主要分析結果。
百濟神州全球研發負責人汪來博士表示:“華氏巨球蛋白血癥是一種慢性、惰性的血液惡性腫瘤,患者的中位生存期可能長達14至16年。因此,對於這些需要長時間治療的患者而言,瞭解治療方案的長期特徵至關重要。在ASPEN試驗的長期隨訪過程中,百悦澤®展現出了持久的疾病緩解及安全性優勢,進一步增強了我們對其安全性和有效性的信心。我們將繼續探索百悦澤®在其他適應症中的使用,從而為更多患者提供可耐受、有效的全新治療選擇。同時,百悦澤®的2期 ROSEWOOD試驗在高風險、復發╱難治性的濾泡性淋巴瘤患者中取得了積極結果,對此我們也深受鼓舞。”
除了公佈百悦澤®最新臨牀試驗結果,百濟神州還將在6月5日的摘要更新會議上對其早期開發管線以及百澤安® (替雷利珠單抗)3期臨牀試驗RATIONALE 309的結果進行海報展示。RATIONALE 309是一項3期臨牀試驗,評估百澤安®聯合化療對比安慰劑聯合化療,用於一線治療復發或轉移性鼻咽癌患者的效果。這些結果已在2022年4月19日的ASCO全體大會系列會議上進行了初步展示:百濟神州公佈3期臨牀試驗RATIONALE-309的更新結果。
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