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永泰生物-B(06978.HK):迪諾侖賽注射液一期臨牀試驗首例患者入組
格隆匯 11-07 17:34

格隆匯11月7日丨永泰生物-B(06978.HK)宣佈,公司已於2023年11月7日在中國完成迪諾侖賽注射液("DCI")一期臨牀試驗的首例患者入組,標誌着集團在研產品開發的里程碑。DCI(原稱RC19D2、CAR-T-19-D2及CAR-T-19-DNR)為靶向CD19抗原且拮抗TGF-ß下游信號通路的蛋白,用於治療患有復發難治瀰漫性大B細胞淋巴瘤("DLBCL")的患者之注射液。該注射液的目標為解決嵌合抗原受體T細胞("CAR-T細胞")對實體瘤治療的持久性不夠、治療效果欠佳及預防腫瘤復發的痛點。根據DCI的臨牀試驗進展,預計目標患者招募將於2024年年底完成,並將於2025年上半年公佈初步分析及結果。

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