歌禮製藥(01672.HK)新冠口服抑制劑新藥臨床試驗申請獲內地受理
歌禮製藥-B(01672.HK)公布,其新冠口服候選藥物聚合(酉每)(RdRp)抑制劑ASC10新藥臨床試驗(IND)申請,已獲國家藥監局受理。
ASC10是一款口服雙前藥,同單前藥莫努匹韋(molnupiravir)相比具有新的差異化的化學結構。口服給藥後,ASC10和莫努匹韋均可在體內快速、完全轉換為相同的活性代謝物ASC10-A,也稱β-D-N4-羥基胞(甘)(NHC)。
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