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三葉草生物-B(02197.HK)新冠候選疫苗作為同源加強針令Omicron BA.2抗體水平提升19倍
阿思達克 06-27 17:36
三葉草生物-B(02197.HK)公布,初步分析結果顯示,接種第三劑SCB-2019(CpG1018/鋁佐劑)同源加強針的個體對奧密克戎(Omicron)變異株的新的積極臨床資料。基線血清陰性受試者接種SCB-2019(CpG1018/鋁佐劑)同源加強針,對奧密克戎變異株BA.2的中和抗體水平比接種加強針之前顯著提升19倍,對奧密克戎變異株BA.1的中和抗體提升12倍。 該項雙盲、隨機、對照的研究評估了基礎免疫接種2劑SCB-2019(CpG1018/鋁佐劑)約6個月後接種同源加強針的免疫原性和安全性。該研究在巴西、菲律賓和哥倫比亞共招募了3,755名受試者。 公司指,將繼續專注於2022年下半年完成向中國國家藥品監督管理局、歐洲藥品管理局和世界衛生組織遞交SCB-2019(CpG1018/鋁佐劑)的註冊申請,同時為全球商業化做準備。
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