和鉑醫藥(02142.HK)兩項試驗完成向首名患者給藥
和鉑醫藥-B(02142.HK)公布,公司在HBM4003臨床I期試驗中,完成向首名患者就治療晚期肝細胞癌及其他實體瘤以及治療晚期神經內分泌腫瘤及其他實體瘤的兩項首次給藥。
HBM4003為公司開發的下一代抗CTLA-4全人源重鏈抗體(HCAb)。本臨床研究旨在評估綜合使用HBM4003及托瑞帕利單抗(PD-1抗體)對中國肝細胞癌、神經內分泌腫瘤及其他實體瘤患者的安全性、耐受性、藥代動力學/藥效學及初步療效。
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