百濟神州(06160.HK)與SpringWorks共同成立MapKure專注開發腫瘤生長抑制劑
百濟神州(06160.HK)與SpringWorks Therapeutics宣布成立MapKure, LLC,由雙方共同擁有。
MapKure的創立旨在開發BGB-3245,一款針對特定單聚體和二聚體B-RAF啟動突變型的在研口服高選擇性小分子抑制劑。
BGB-3245抑制的B-RAF突變-包括B-RAF V600突變型,B-RAF非V600突變型和RAF融合-這些突變在包括非小細胞肺癌(NSCLC)、結直腸癌(CRC)、甲狀腺癌及腦腫瘤的多項實體瘤中被認定為腫瘤的生長提供了動力。
BGB-3245由百濟神州科學家自主研發,目前處於臨床前開發階段。根據合作條款,SpringWorks已對MapKure進行股權投資;百濟神州則貢獻了在亞洲以外國家和地區(包括日本)開發及商業化BGB-3245的獨家版稅和里程碑授權,以換取MapKure的多數擁有權。
Follow us
Find us on
Facebook,
Twitter ,
Instagram, and
YouTube or frequent updates on all things investing.Have a financial topic you would like to discuss? Head over to the
uSMART Community to share your thoughts and insights about the market! Click the picture below to download and explore uSMART app!

Disclaimers
uSmart Securities Limited (“uSmart”) is based on its internal research and public third party information in preparation of this article. Although uSmart uses its best endeavours to ensure the content of this article is accurate, uSmart does not guarantee the accuracy, timeliness or completeness of the information of this article and is not responsible for any views/opinions/comments in this article. Opinions, forecasts and estimations reflect uSmart’s assessment as of the date of this article and are subject to change. uSmart has no obligation to notify you or anyone of any such changes. You must make independent analysis and judgment on any matters involved in this article. uSmart and any directors, officers, employees or agents of uSmart will not be liable for any loss or damage suffered by any person in reliance on any representation or omission in the content of this article. The content of this article is for reference only. It does not constitute an offer, solicitation, recommendation, opinion or guarantee of any securities, financial products or instruments.The content of the article is for reference only and does not constitute any offer, solicitation, recommendation, opinion or guarantee of any securities, virtual assets, financial products or instruments. Regulatory authorities may restrict the trading of virtual asset-related ETFs to only investors who meet specified requirements.
Investment involves risks and the value and income from securities may rise or fall. Past performance is not indicative of future performance.